Data access

Visual abstract alternative splicing

Single-cell mapping of alternative splicing linked to checkpoint immunotherapy response

Single-Cell Analysis of Unresectable Non-metastatic Locally Advanced Pancreatic Cancer after Minimally Invasive Surgical Microwave Ablation plus Durvalumab and Tremelimumab

FSGS

Single-Nucleus RNA-Sequencing Identifies a Differential Profibrotic Response in Parietal Epithelial Cells in Primary Versus Maladaptive Focal Segmental Glomerulosclerosis

Cover Fra

Decoding tumor heterogeneity: A spatially informed pan-cancer analysis of the tumor microenvironment

Sex cord tumors

Single-cell profiling in ovarian germ cell and sex cord-stromal tumours

Elst et al

Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization

Rubiks

CD4+ T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 from anti-PD-L1 monotherapy

COVID-19-associated pulmonary aspergillosis

Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study

HCC

PD-1 negative CD45RA effector-memory CD8 T-cells are essential for response to checkpoint inhibition in advanced hepatocellular carcinoma

Pneumonitis

Single-cell transcriptomics identifies pathogenic T-helper 17.1 cells and pro-inflammatory monocytes in immune checkpoint inhibitor-related pneumonitis

single cell zwart

A Single-cell Map of Intratumoral Changes during Anti-PD1 Treatment of Patients with Breast Cancer

Immune atlas of COVID-19 Bronchoalveolar Lavages

Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

PBMC COVID

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

Workflow

High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification

tme

A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling